Oligodendroglial Tumors Frequently Demonstrate Hypermethylation of theCDKN2A(MTS1, p16INK4a),p14ARF, andCDKN2B(MTS2,p15INK4b) Tumor Suppressor Genes
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چکیده
منابع مشابه
Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in oligodendroglial tumors
Aberrant methylation has been associated with transcriptional inactivation of tumor-related genes in a wide spectrum of human neoplasms. The influence of DNA methylation in oligodendroglial tumors is not fully understood. Genomic DNA was isolated from 61 oligodendroglial tumors for analysis of methylation using methylation-specific multiplex ligation-dependent probe amplification assay (MS-MLPA...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2001
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/60.12.1170